Surgical Treatment in Hypertension *From an address by Dr. Horace Evans to the Devon and Exeter Medico-Chirurgical Society on October 26th, 1948.
نویسنده
چکیده
In opening his address the speaker reviewed the history of hypertensive disease. Richard Bright considered hypertension was secondary to nephritis, Sir Clifford Allbutt showed that in the majority of cases there is no clinical evidence to support that view: what he named " hyperpiesia " is now called benign essential hypertension. Goldblatt produced hypertension in the dog by partially occluding one kidney and Wilson and Byrom repeated this experiment on rats and observed histological changes in the opposite kidney: if the clamped kidney was removed early hypertension did not develop. From this it was deduced that the kidney produces a pressor substance; but prolonged search for anti-pressor substances has proved fruitless. Trueta by stimulating the sympathetic produced cortical ischaemia of the kidney with resulting hypertension. There is some difference of opinion as to what constitutes hypertension. The speaker considered that a systolic pressure of 180 mm. Hg. is certainly the upper limit of the normal range?he was inclined to put it lower: a persistent diastolic pressure of 100
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عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 1948